COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions in protein–protein and protein–nucleic acid complexes
COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions in protein–protein and protein–nucleic acid complexes
Bioinformatics · 2025 · Cited 9 times
Mohit Chawla, Utkarsh Kalra, Andrea Petta, Suraj Sharma, Abdul Rajjak Shaikh, Luigi Cavallo, Romina Oliva
COCOMAPS 2.0 is a free web server for studying how proteins bind to other proteins or to nucleic acids. It maps and visualizes the contact interface between two molecules — which residues touch and how much surface they bury — automating an analysis structural biologists otherwise do by hand. This release adds more comprehensive and accurate interface comparison on top of the original tool’s residue-level and buried-surface-area analysis. For students working on docking or protein complexes, it is a practical way to read and compare binding interfaces without writing custom code.
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