Enhanced Detection of DNA Nucleobases Using a C2O Monolayer Nanodevice: Insights from First-Principles Analysis - StemSkills Lab
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ACS Applied Nano Materials 2025

Enhanced Detection of DNA Nucleobases Using a C2O Monolayer Nanodevice: Insights from First-Principles Analysis

Vasudeo Babar, Sitansh Sharma, Abdul Rajjak Shaikh, Romina Oliva, Mohit Chawla, Luigi Cavallo

Using first-principles (density functional theory) calculations, this study evaluates a C2O monolayer as a nanodevice for detecting the four DNA bases. It examines how each base adsorbs onto the material and how that changes the electronic transport, the signal a sequencing device would read. It adds to the search for fast, low-cost DNA sequencing built on 2D materials.

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Vasudeo Babar, Sitansh Sharma, Abdul Rajjak Shaikh, Romina Oliva, Mohit Chawla, Luigi Cavallo (2025) Enhanced Detection of DNA Nucleobases Using a C2O Monolayer Nanodevice: Insights from First-Principles Analysis. ACS Applied Nano Materials. https://doi.org/10.1021/acsanm.5c03183

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