Tag
Immunoinformatics
Molecular Modeling How to Run an MD Simulation of a Vaccine Construct-TLR Complex in GROMACS: Setup, Length and What to Report Take a docked vaccine construct into GROMACS: which pose to carry forward, force field and box setup, how many replicas to run,… Ragini Mishra 17 min read Bioinformatics How to Dock a Multi-Epitope Vaccine Construct with TLR4: ClusPro, HDOCK and HADDOCK Compared Dock a screened vaccine construct against TLR4 the way a reviewer reads it: pick the PDB entry, prep the files, compare three… Ragini Mishra 16 min read Bioinformatics How to Check Epitope Allergenicity, Toxicity and Antigenicity: VaxiJen, AllerTOP and ToxinPred Screen your epitope shortlist properly: which server to run first, which threshold to set, and what to do with a borderline score.… Ragini Mishra 14 min read Bioinformatics How to Design a Multi-Epitope Vaccine Construct: Linkers, Adjuvant and Order Join your shortlisted epitopes into one designed protein: which linker goes where, why order matters, and how to validate the sequence. Build… Ragini Mishra 14 min read Bioinformatics How to Predict T-Cell Epitopes and MHC Binding with NetMHCpan and IEDB Pick an HLA panel, set the right peptide length, and filter on percentile rank. Turn thousands of NetMHCpan rows into a defensible… Ragini Mishra 17 min read Bioinformatics How to Predict B-Cell Epitopes with BepiPred and ABCpred: A Step-by-Step Guide Run BepiPred and ABCpred on the same antigen, read per-residue scores against the threshold, and keep only consensus peptides. Start with this… Ragini Mishra 15 min read Career Guide Career Opportunities After BSc Life Sciences in 2025: The Ultimate Guide 1. Introduction: Why 2025 Is the Best Time to Build a Career in Life Sciences If you are graduating with a BSc… Dr. Abdul Rajjak Shaikh 8 min read Updated Bioinformatics Immunoinformatics: What It Is and How It’s Helping Design Smarter Vaccines Vaccines are among the greatest achievements in medical science, saving millions of lives every year. But did you know the way we… Dr. Abdul Rajjak Shaikh 3 min read Updated Publications Synthesis, quantum mechanical calculations, molecular docking, Hirshfeld surface analysis and ADMET estimation studies Abstract Synthesis, crystallographic characterization, spectroscopic (FT-IR, UV-Vis, NMR) and density functional studies of (E)-3-(anthracene-10-yl)-1-(napthalen-1-yl)prop-2-en-1-one (3ANP) have been reported. The molecular structure obtained… Stemskills Lab 2 min read Updated Publications Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases|Research Paper by StemSkill Lab Abstract Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is… Stemskills Lab 1 min read Updated