Sensing the Artificially Expanded Genetic Information System DNA Using Janus MoSSe Monolayers: A Density Functional Theory Investigation
Sensing the Artificially Expanded Genetic Information System DNA Using Janus MoSSe Monolayers: A Density Functional Theory Investigation
- June 14, 2026
- Posted by: Stemskills Lab
ACS Applied Nano Materials · 2026 · Cited 1 times
Sitansh Sharma, Vasudeo Babar, Abdul Rajjak Shaikh, Hosna Jabbari, Romina Oliva, Mohit Chawla, Luigi Cavallo
This computational study tests whether a Janus MoSSe monolayer — an atomically thin two-dimensional material — can detect the bases of Hachimoji DNA, an artificial genetic system that extends DNA’s usual four letters to eight. Using density functional theory, the team examined how each base binds to the material and how that shifts its electronic signal. The work feeds a wider effort to build cheap, label-free DNA-sequencing devices from 2D materials.
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