Vaccine Design

Vaccines are among the greatest achievements in medical science, saving millions of lives every year. But did you know the way we design vaccines is rapidly changing, thanks to a new digital discipline called immunoinformatics? This field blends immunology with computational science to create better, faster, and safer vaccines—ushering in a new era for public […]

Abstract Canine circovirus (CanineCV) is a deadly pathogen affecting both domestic and wild carnivores, including dogs. No vaccine against CanineCV is available commercially or under clinical trials. In the present study, we have designed a promising multiepitope vaccine (MEV) construct targeting multiple strains of CanineCV. A total of 545 MHCII binding CD4+T cell epitope peptides […]

Abstract Dengue virus (DENV) is an arboviral disease affecting more than 400 million people annually. Only a single vaccine formulation is available commercially and many others are still under clinical trials. Despite all the efforts in vaccine designing, the improvement in vaccine formulation against DENV is very much needed. In this study, we used a roboust […]