Frontiers in Veterinary Science 2025
Feline immunodeficiency virus: current insights into pathogenesis, clinical impact, and advances in treatment and vaccine development.
Nahid Akhtar, Ragini Mishra, Shivakant Tripathi, Santiago Redon-Marin, Manik Prabhu Narsing Rao, Andrés Felipe Cuspoca Orduz, Jorge Samuel Leon Magdaleno, Abdul Rajjak Shaikh, Julian Ruiz-Saenz, Luigi Cavallo, Mohit Chawla
This review brings together current knowledge on feline immunodeficiency virus (FIV), a retrovirus that progressively weakens the immune system of domestic and wild cats. It covers how the virus spreads, the disease it causes, its subtypes and clinical effects, and how infected cats are managed. It also surveys progress and the real challenges in developing antiviral treatments and an effective FIV vaccine, including the adjuvants under study.
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Nahid Akhtar, Ragini Mishra, Shivakant Tripathi, Santiago Redon-Marin, Manik Prabhu Narsing Rao, Andrés Felipe Cuspoca Orduz, Jorge Samuel Leon Magdaleno, Abdul Rajjak Shaikh, Julian Ruiz-Saenz, Luigi Cavallo, Mohit Chawla (2025) Feline immunodeficiency virus: current insights into pathogenesis, clinical impact, and advances in treatment and vaccine development.. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2025.1665999
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