Bioinformatics

Introduction Molecular dynamics, a fascinating intersection of physics and chemistry, offers a microscopic view into the behavior of atoms and molecules. As its significance in scientific research grows, students and professors are increasingly eager to delve into its complexities. This guide aims to illuminate the intricate world of molecular dynamics simulations for the academic community. […]

Bioinformatics, often described as the intersection of biology and computational technology, has rapidly evolved into a pivotal scientific discipline. With the surge in biological data, particularly from genome sequencing projects, the demand for advanced tools and methodologies to decipher this data is more pressing than ever. What Exactly is Bioinformatics? Bioinformatics is the science of […]

A Ph.D. in Bioinformatics is a graduate program focusing on developing and applying computational methods and technologies to solve biological problems. This program typically involves advanced coursework in bioinformatics and original research that contributes to the field of bioinformatics. To be eligible for a Ph.D. in Bioinformatics, you typically need a master’s degree in a […]

Drug design is the process of using computational methods and technologies to identify and develop new drugs that can be used to treat various diseases. This process involves several steps, and multiple tools and resources are used to facilitate and improve the efficiency of drug design. One of the first steps in drug design is […]

What is bioinformatics? Bioinformatics is the field of science that involves the use of computer technology to analyze and interpret biological data, such as DNA and protein sequences. What is the importance of bioinformatics? Bioinformatics plays a crucial role in advancing the field of biology by allowing researchers to store, analyze, and interpret large amounts […]

Abstract Synthesis, crystallographic characterization, spectroscopic (FT-IR, UV-Vis, NMR) and density functional studies of (E)-3-(anthracene-10-yl)-1-(napthalen-1-yl)prop-2-en-1-one (3ANP) have been reported. The molecular structure obtained from single crystal X-ray diffraction method of the investigated compound was compared with theoretical values by DFT method at B3LYP with 6-311G(d,p) basis set. The 3ANP crystallizes in triclinic space group P1 with […]

Abstract Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is a hallmark of cancer; terminal sialic acid and fucose in particular have high levels in tumor cells, with positive implications for malignancy. Increased sialylation and fucosylation are due to the upregulation of a […]

Abstract Canine circovirus (CanineCV) is a deadly pathogen affecting both domestic and wild carnivores, including dogs. No vaccine against CanineCV is available commercially or under clinical trials. In the present study, we have designed a promising multiepitope vaccine (MEV) construct targeting multiple strains of CanineCV. A total of 545 MHCII binding CD4+T cell epitope peptides […]

Abstract Dengue virus (DENV) is an arboviral disease affecting more than 400 million people annually. Only a single vaccine formulation is available commercially and many others are still under clinical trials. Despite all the efforts in vaccine designing, the improvement in vaccine formulation against DENV is very much needed. In this study, we used a roboust […]